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Gamers must become agents of a pandemic where they must give birth to this pathogen by developing a deadly global Plague while adapting to everything humans can do to defend themselves.

It has become a unique game because of the high strategy integration and the simulation is so realistic that the CDC even asked the developers to come and talk about the infection model in the game.

is a unique blend of high strategy and extremely thrilling realistic simulation which is a real-time strategy simulation video game. Although my hand-crafted plague killed over 6 billion people, some crafty New Zealanders were able to keep their scalps unmolested.Plague Inc. In the end, "Itchyhead" failed to destroy civilization. He hinted at the possibility of movie tie-ins for future games in the franchise, but is currently focused on adding zombies to the game in the next major update. Vaughan plans on expanding his company once he's done tweaking and updating Plague Inc. It put players in control of world health organizations and had them fight ever-evolving diseases using a variety of tools – a reversal of the role a player takes in Pandemic and Plague Inc. In 1985 a PC game called Contamination, possibly the grandaddy of the "global disease simulation genre," was released. Then again, Pandemic was not entirely original, either. " is, unquestionably the better game," critic Simon Parkin wrote in May, "but it is also unquestionably a game that wouldn’t exist were it not for Pandemic." "I thought, 'I like Pandemic 2 but it could be so much better,'" Vaughan said.